Eugene was born and raised in the Philadelphia, Pennsylvania area. He began his acting career as a child in 1986, and has had roles in film, television, and video games.
The following is a partial list of some of Eugene Byrd's notable roles:
- Bones - Dr. Clark Edison.
- Arrow - Andy Diggle
- Gears of War - Delmont "Del" Walker
- Lego Star Wars: The Freemaker Adventures - Zander Freemaker